Neurobiology and Behavior (NEURBIO)

Courses

NEURBIO 200A. Research in Neurobiology and Behavior. 2-12 Units.

Individual research with Neurobiology and Behavior faculty.

Repeatability: Unlimited as topics vary.

Restriction: Graduate students only. Neurobiology and Behavior Majors only.

NEURBIO 200B. Research in Neurobiology and Behavior. 2-12 Units.

Individual research with Neurobiology and Behavior faculty.

Prerequisite: NEURBIO 200A

Repeatability: Unlimited as topics vary.

Restriction: Graduate students only. Neurobiology and Behavior Majors only.

NEURBIO 200C. Research in Neurobiology and Behavior. 2-12 Units.

Individual research with Neurobiology and Behavior faculty.

Prerequisite: NEURBIO 200B

Repeatability: Unlimited as topics vary.

Restriction: Graduate students only. Neurobiology and Behavior Majors only.

NEURBIO 201A. Research in Neurobiology and Behavior. 2-12 Units.

Individual research with Neurobiology and Behavior faculty.

Grading Option: Satisfactory/unsatisfactory only.

Repeatability: Unlimited as topics vary.

Restriction: Graduate students only. Neurobiology and Behavior Majors only.

NEURBIO 201B. Research in Neurobiology and Behavior. 2-12 Units.

Individual research with Neurobiology and Behavior faculty.

Prerequisite: NEURBIO 201A

Grading Option: Satisfactory/unsatisfactory only.

Repeatability: Unlimited as topics vary.

Restriction: Graduate students only. Neurobiology and Behavior Majors only.

NEURBIO 201C. Research in Neurobiology and Behavior. 2-12 Units.

Individual research with Neurobiology and Behavior faculty.

Prerequisite: NEURBIO 201B

Grading Option: Satisfactory/unsatisfactory only.

Repeatability: Unlimited as topics vary.

Restriction: Graduate students only. Neurobiology and Behavior Majors only.

NEURBIO 202A. Foundations of Neuroscience. 2 Units.

Intended to expose students to critical reading and analysis of the primary neuroscience literature. Instructors from departments associated with the Interdepartmental Neuroscience Program participate and discuss topics of current interest.

Grading Option: Satisfactory/unsatisfactory only.

NEURBIO 202B. Foundations of Neuroscience. 2 Units.

Intended to expose students to critical reading and analysis of the primary neuroscience literature. Instructors from departments associated with the Interdepartmental Neuroscience Program participate and discuss topics of current interest.

Prerequisite: NEURBIO 202A

Grading Option: Satisfactory/unsatisfactory only.

NEURBIO 206. Molecular Neuroscience. 5 Units.

Surveys molecular and cellular mechanisms involved in neuronal function, including control of gene expression, post-transcriptional and post-translational processing, RNA and protein targeting, cell death mechanisms, and molecular genetic basis of neurological disorders. Overview of the molecular aspects of developmental neurobiology.

Restriction: Graduate students only. Neurobiology and Behavior Majors only.

NEURBIO 207. Cellular Neuroscience. 5 Units.

Neurophysiological and neurochemical mechanisms of electrical and chemical signaling in neurons. Topics include generation of resting- and action-potentials, voltage- and ligand-gated ion channels, second messenger systems, and synaptic transmission and integration.

Restriction: Graduate students only. Neurobiology and Behavior Majors only.

NEURBIO 207L. Cellular Neuroscience Laboratory. 2 Units.

Intensive hands-on laboratory experience of contemporary techniques for studying ion channels and synaptic function. Experiments include microelectrode recording, patch clamp, quantal analysis of synaptic transmission, heterologous expression of genes for channels and receptors, brain slice, and fluorescence calcium imaging.

Grading Option: Satisfactory/unsatisfactory only.

Restriction: Graduate students only. Neurobiology and Behavior Majors only.

NEURBIO 208A. Systems Neuroscience. 5 Units.

Study of the mammalian nervous system at the systems level. Anatomy and physiology of sensory, motor, and integrative functions.

Repeatability: May be taken for credit 2 times.

Same as ANATOMY 210A.

Restriction: Graduate students only. Neurobiology and Behavior Majors only.

NEURBIO 209. Behavioral Neuroscience. 5 Units.

Overview of fundamental conceptual and experimental issues in the neurobiology of learning and memory. The approach is a cross-level integration of research in molecular-genetic, cellular, circuit, systems, and behavioral analyses.

Restriction: Graduate students only. Neurobiology and Behavior Majors only.

NEURBIO 220. Neural Coding, Computation, and Dynamics. 4 Units.

Theoretical principles and biological mechanisms underlying how brains acquire, assimilate, store, and retrieve information, compute adaptive responses to external inputs, and how knowledge is extracted from experience to generate an internal model of the world.

Prerequisite: At least one upper-division course in the field of Neuroscience or one upper-division course in Cognitive Science or Machine Learning.

NEURBIO 221. Scientific Presentation Skills. 1 Unit.

A tutorial seminar on developing skills for presenting research to scientific audiences.

Grading Option: Satisfactory/unsatisfactory only.

Restriction: Graduate students only.

NEURBIO 225. Rigor, Reproducibility, and Research Methods. 1 Unit.

Understanding key concepts in experimental design, execution, and analysis that enhance or detract from scientific rigor.

Grading Option: Satisfactory/unsatisfactory only.

Restriction: Graduate students only.

NEURBIO 230. Epigenetics in Health and Disease . 4 Units.

Focuses on the role of chromatin/nuclear structure organization (histone and DNA modification, chromatin remodeling, higher order chromatin structure and nuclear organization) on gene regulation, DNA replication and repair, relevant to development, metabolism, learning and memory, and human disease.

Prerequisite: MOL BIO 203 or MOL BIO 204 or NEURBIO 206

Same as BIOCHEM 225.

Restriction: Graduate students only.

NEURBIO 231. Clinical and Epidemiological Aspects of Neurodegenerative Diseases. 4 Units.

Clinical and epidemiological aspects of neurodegenerative disorders causing dementia will be reviewed, including AD, PD, FTD, HD and cerebrovascular disease. Seminar format will include student presentations and group discussion.

Restriction: Graduate students only.

NEURBIO 232. Regenerative Neurobiology. 4 Units.

Surveys the latest research on regenerative neurobiology. Both basic stem cell discoveries and their potential clinical application to brain disorders will be examined.

NEURBIO 233. Neurobiology of Drug Addiction. 4 Units.

Provides a comprehensive overview of topics in the addiction field, including drug pharmacology, models/approaches to investigate addiction, brain circuits, genetics, epigenetics, and the cellular and molecular biology of drug addiction.

Restriction: Graduate students only.

NEURBIO 234. Cognitive Neuroepigenetics. 4 Units.

Covers current topics in the emerging field of cognitive neuroepigenetics, focusing on understanding the underlying epigenetic mechanisms of memory formation and persistence. Primary literature will be used to explore these processes.

Repeatability: May be repeated for credit unlimited times.

NEURBIO 235. Balancing Research and Teaching. 1 Unit.

The goal of this course is to offer graduate students who have commitments outside of their research program (such as teaching) an opportunity to learn to balance these commitments.

NEURBIO 236. Cortex: Structure, Function, and Plasticity. 4 Units.

Structured to include lectures and presentation of papers about cortex with emphasis on sensory-motor cortex. Both historical and current perspectives on cortical structure-function relationship will be critically evaluated.

NEURBIO 237. Neurobiology of Brain Aging. 4 Units.

Outlines some of the significant changes that occur in the aging brain, with a special emphasis on risk factors and protective strategies that promote successful brain aging. Topics include changes in synaptic plasticity, neurotrophic factors, and molecular mechanisms in aging.

Prerequisite: NEURBIO 209

NEURBIO 239. Functional Imaging of the Nervous System. 4 Units.

Overview of technical and applied aspects of imaging techniques available for studying the nervous system. The areas emphasized are cellular and subcellular imaging of neural function, systems-level imaging of brain function, and imaging of the human brain.

Restriction: Graduate students only. Neurobiology and Behavior Majors only.

NEURBIO 240. Advanced Analysis of Learning and Memory. 4 Units.

Advanced analysis of contemporary research concerning the nature and neurobiological bases of learning and memory. Special emphasis is given to time-dependent processes involved in memory storage.

Restriction: Graduate students only. Neurobiology and Behavior Majors only.

NEURBIO 247. Programming for Neuroscience Research . 4 Units.

A neuroscience-specific introduction to programming and data analysis using either MATLAB or Scientific PYTHON. Students will learn general programming skills and effective use of programming for data management, statistical analysis, and image analysis.

Overlaps with PSYCH 205A.

NEURBIO 248. Topics in Neurobiology and Behavior. 4 Units.

Studies in selected areas of Neurobiology and Behavior. Topics addressed vary each quarter.

Repeatability: May be taken for credit 3 times.

NEURBIO 249. Electronics for Biologists. 4 Units.

Basic principles of electricity; properties and use of discrete components and integrated circuits; circuit analysis and design. Intended for advanced students in the life sciences.

Same as PHYSIO 205.

NEURBIO 254. Molecular Neurobiology. 4 Units.

The application of genetic and recombinant DNA technology to neurobiology. Topics include the study of neuronal proteins which play important roles in the formation of synapses and synaptic transmission.

Restriction: Graduate students only. Neurobiology and Behavior Majors only.

NEURBIO 255. History of Neuroscience. 4 Units.

An overview of the conceptual and technical foundations of contemporary neuroscience from ancient times to the present. The subjects include synapses, neurons, brain organization, sensory, motor and regulatory systems, learning and memory, human brain function and dysfunction.

Repeatability: May be taken for credit 2 times.

Restriction: Graduate students only. Neurobiology and Behavior Majors only.

Concurrent with BIO SCI N119.

NEURBIO 257. Statistics for Neurobiologists. 4 Units.

IIntroduction to common methods for statistical analysis used in neurobiology. Topics covered include t-tests, ANOVAs, correlations and regressions, general linear model, power analysis, and non-parametric tests.

Restriction: Graduate students only. Neurobiology and Behavior Majors only.

NEURBIO 260. Auditory Neuroscience. 4 Units.

Multidisciplinary overview of brain mechanisms of hearing. Emphasizes breadth of auditory function and research: single neurons to psychoacoustics, the chochlea to the cortex, and basic science to clinic.

Concurrent with BIO SCI N147.

NEURBIO 290. Colloquium in Neurobiology and Behavior. 1.3 Unit.

Presentation of contemporary research problems in neurobiology and behavior and related areas by invited speakers.

Grading Option: Satisfactory/unsatisfactory only.

Repeatability: May be repeated for credit unlimited times.

Restriction: Graduate students only. Neurobiology and Behavior Majors only.

NEURBIO 292. Scientific Communication. 4 Units.

Students learn how to effectively communicate scientific ideas and results. Activities include learning how to effectively write a scientific proposal, how to perform a coherent, persuasive slide presentation, and how to give meaningful, constructive review critiques.

Restriction: Graduate students only. Neurobiology and Behavior Majors only.

NEURBIO 399. University Teaching. 1-4 Units.

Limited to Teaching Assistants.

Repeatability: May be repeated for credit unlimited times.

Restriction: Graduate students only.

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