2024-25 Edition

Microbiology and Immunology, B.S.

Microbiology and immunology are well-established disciplines within the life sciences. Microbiology addresses the biology of bacteria, viruses, and unicellular eukaryotes such as fungi and protozoa. Studies of microorganisms reveal basic information about processes in evolution, genetics, biochemistry, molecular biology, cell biology, structural biology, and ecology. Many bacteria, viruses, and protozoa cause disease in plants and animals. Hence, major areas of medicine and public health focus on these microorganisms.

Much of our knowledge in microbiology comes from the study of prokaryotic organisms, particularly bacteria. In addition to their relevance to infectious disease, these streamlined organisms provide a look at the basic requirements for life. The study of bacterial genetics has resulted in the creation of many genetic tools that are now used frequently to modify and study other organisms. Bacteria can also play an important role in the production of important materials such as biofuels and biopharmaceuticals. Understanding the behaviors of natural communities of bacteria and other organisms, called microbiomes, is an emerging field in our understanding of human health and disease. 

The study of viruses (virology) is an important branch of microbiology that has contributed to our understanding of most of the fundamental processes in eukaryotic molecular biology, including the discovery of oncogenes. Viruses provide an excellent tool for the study of disease, cancer, and mechanisms of gene control. With the growing threat of emerging diseases, including global pandemics, and the potential for viral-based biological weapons, the study of virology has recently intensified and gained new perspectives.

Immunology encompasses efforts to understand how multicellular organisms have evolved to survive a variety of challenges to health and survival, including threats by pathogens and cancer cells. This includes an understanding of how the immune system develops, is activated, responds, and shuts down.  Basic questions of how immunity functions are entwined with a fundamental understanding of the consequences of microbial infection, in a field called host-pathogen interactions. Immunology also encompasses the study of autoimmunity, the attack of the host by its own immune system, as well as the prevention of a response, known as immunological tolerance.  

The major has been designed to span the interconnected disciplines of Microbiology and Immunology, and students have the opportunity to select courses from any of the following three areas: microbiology, immunology, or virology. The curricula overlap considerably, but there are unique courses for each discipline. The major is designed primarily for students who are serious about pursuing careers in microbiology and immunology and is intended to provide its graduates with the appropriate tools and training to successfully pursue professional and graduate degrees emphasizing these disciplines. These include Ph.D., M.D., and combined M.D./Ph.D. programs. Majoring in Microbiology and Immunology will also provide resources for serious students wishing to use a solid background in these disciplines for career goals in business, law, public and environmental policy, education, and other pursuits.

Application Process to Declare the Major: The major in Microbiology and Immunology is open to junior- and senior-level students only. Applications to declare the major can be made at the end of spring quarter, after all change of major requirements have been satisfied. Review of applications submitted at that time and selection to the major by the Microbiology and Immunology Faculty Board is completed during the summer. Information can also be found at the UCI Change of Major Criteria website. Double majors within the School of Biological Sciences or with Public Health Sciences, Biomedical Engineering: Premedical, Nursing Science, or Pharmaceutical Sciences are not permitted.

All students must meet the University Requirements.
All students must meet the School Requirements.
Major Requirements for Microbiology and Immunology
A. Required Major Courses:
BIO SCI M121 Immunology with Hematology
BIO SCI M122 General Microbiology
BIO SCI M124A Virology
B. Upper-Division Laboratories:
Select two from:
Molecular Biology Laboratory
Experimental Microbiology Laboratory
Advanced Immunology Laboratory
C. Upper-Division Biology Electives:
C1. Select at least four from the following:
Intercellular Signaling and Disease
Human Physiology
Parasitology
Microbiomes
Advanced Topics in Immunology
Viral Pathogenesis and Immunity
Molecular Biology of Cancer
Innate Immunity, Infection, and Pathogenesis
Microbial Genetics
Human Parasitology
Vascular Biology: Blood Vessels in Health and Disease
Biotechnological Applications of Energy and Environmental Research
Foundations in Neuroimmunology
Molecular Virology
C2. Select two from C1 or the following:
Cell Biology
Eukaryotic and Human Genetics
Advanced Biochemistry
Advanced Molecular Biology
Cell Organelles and Membranes
NOTE: No course may be used to satisfy more than one requirement.

Application Process to Declare the Major: The major in Microbiology and Immunology is open to junior- and senior-level students only. Applications to declare the major can be made at any time, but typically in the spring of the sophomore year. Review of applications submitted at that time and selection to the major by the Microbiology and Immunology Faculty Board is completed during the summer. Information can also be found at the UCI Change of Major Criteria website. Double majors within the School of Biological Sciences or with Public Health Sciences, Biomedical Engineering: Premedical, Nursing Science, or Pharmaceutical Sciences are not permitted.

Freshman
Fall Winter Spring
BIO SCI 93BIO SCI 94CHEM 1C- 1LC
BIO SCI 93LBIO SCI 94LSTATS 7, 8, or MATH 5A (or General Education)
CHEM 1ACHEM 1BLower-Division Writing1
General EducationLower-Division Writing1 
BIO SCI 2AGeneral Education 
Sophomore
Fall Winter Spring
BIO SCI 97BIO SCI 98BIO SCI 99
CHEM 51ACHEM 51B- 51LBCHEM 51C- 51LC
CHEM 1LDMATH 5B (or General Education)General Education
MATH 5A or 5B  
Junior
Fall Winter Spring
PHYSICS 3APHYSICS 3B- 3LBPHYSICS 3C- 3LC
BIO SCI M124AU-D Bio ElectiveBIO SCI M122
BIO SCI 100BIO SCI M121General Education or U-D Lab
BIO SCI 199BIO SCI 199BIO SCI 199
Senior
Fall Winter Spring
U-D Biology ElectiveU-D Biology ElectiveU-D Biology Elective
BIO SCI M116LU-D Biology ElectiveU-D Biology Elective
BIO SCI 199BIO SCI 199BIO SCI 199
1

Students have the option of taking HUMAN 1AS, HUMAN 1BS, HUMAN 1CS or WRITING 40, WRITING 50, WRITING 60 in order to fulfill the lower-division writing requirement.