Weekly meetings consisting of presentations by faculty, professional staff, and Peer Academic Advisors provide information about the Pharmaceutical Sciences major, campus resources, learning skills, and special programs and opportunities.

Grading Option: Pass/no pass only.

Restriction: Pharmaceutical Sciences Majors only. New students only.

Designed to help Pharmaceutical Science majors select a career track and prepare for graduate program applications and careers in industry.

Grading Option: Workload Credit P/NP Only.

Restriction: Pharmaceutical Sciences Majors only.

Covers the latest scientific work on the impact of nutrition, exercise, and lifestyle choices on mental and physical health. Motivates students to make positive changes by fostering personal growth.

Covers the ethical responsibilities of biomedical scientists. Topics include, as discussions and case studies, the high standards of science, the responsible conduct of research, animal experimentation, and clinical trials as they relate to the pharmaceutical sciences.

Where drugs come from, how drugs work, how and why people abuse drugs, the costs of drug abuse on society, which drugs are commonly abused, and how drug abuse can be prevented and treated. Course intended for non-science majors.

Prerequisite: Recommended: High school chemistry and biology.

Restriction: Campuswide Honors Collegium students only.

(II)

Students learn to effectively prepare and present public speeches and slide presentations. Included are storytelling, informative, commemorative, and persuasive speeches, and scientific presentation. Evaluating speeches and strategies to reduce speaker apprehension is also covered.

Restriction: Pharmaceutical Sciences Majors have first consideration for enrollment.

Covers the function of the human body. All major organ systems are discussed. Designed to prepare students for healthcare careers, such as medicine, pharmacy, dentistry, and for research careers which require basic knowledge of how the human body functions.

Corequisite: PHRMSCI 120L
Prerequisite: BIO SCI 99

Overlaps with BIO SCI E109.

Designed to complement PHRMSCI 120. Computer-based lab simulations are used to study the function of the human body. Class physically meet for review sessions and exams.

Corequisite: PHRMSCI 120
Prerequisite: BIO SCI E109

Overlaps with BIO SCI E112L.

An introduction to the structure, metabolism, cultivation, isolation, classification, and identification of the major groups of bacteria. Additional focus on identification of infection and use of antibiotics in diseased patients.

Prerequisite: BIO SCI 99 and CHEM 51C. CHEM 51C with a grade of C- or better

Covers the complex and multi-factorial process of aging and increases the understanding of factors that contribute to enhanced lifespan, including basic principles of health and wellness and scientifically proven interventions, both pharmacological and non-pharmacological.

Prerequisite: BIO SCI 98 and BIO SCI 99 and PHRMSCI 120

Restriction: Upper-division students only.

Mechanisms underlying chemical signaling processes in the nervous system. Fundamental knowledge for understanding the cellular and molecular actions of drugs and their mechanisms of action on synaptic transmission. Applied neuropsychopharmacology including major drug classes and therapeutic uses.

Prerequisite: PHRMSCI 170A. PHRMSCI 170A with a grade of C- or better

Restriction: Upper-division students only.

Survey of the genetic and epigenetic basis of inter-subject variability in response to drugs. Covers drug efficacy, safety, and need for their optimization in pharmacotherapy. Emphasizes genetic mechanisms of polymorphisms in the pharmacokinetics and pharmacodynamics of representative therapeutic drugs.

Prerequisite: BIO SCI 99

Concurrent with PHRMSCI 263.

Molecular basis of drug-receptor action at the molecular and cellular levels. Structure-function of drug targets emphasizing enzymes, ion channels, and membrane transport proteins. Understanding how the drugs' mechanisms of action contribute to the development of more efficacious and safer drugs.

Prerequisite or corequisite: (CHEM 51C or CHEM H52C) and (PHRMSCI 120 or BIO SCI E109)

Restriction: Pharmaceutical Sciences Majors have first consideration for enrollment.

Introductory survey covering the molecular mechanisms of drugs that target the nervous system, such as anxiolytics, antidepressants, antipsychotics, hypnotics, muscle relaxants, and recreational drugs; drugs related to the immune system, including antibiotics, antihistamines, and immunosuppressants; drugs used to treat cancer.

Prerequisite: PHRMSCI 170A

Thermodynamics and kinetic fundamentals as applied to problems relevant to pharmaceutical sciences such as receptor/enzyme-ligand interactions. Fundamentals of biophysical methods used in the pharmaceutical sciences including structure determination and biomolecular spectroscopy.

Prerequisite: MATH 2B and PHYSICS 3C and (CHEM 1C or CHEM H2C) and BIO SCI 99

Restriction: Pharmaceutical Sciences Majors have first consideration for enrollment.

Presents information about various fields of research, study, careers, and graduate school opportunities in pharmaceutical sciences. Taught by guest lecturers from various disciplines including 199 research course faculty. Helps Pharmaceutical Sciences students select electives appropriate to their future goals.

Prerequisite or corequisite: BIO SCI 99 and (CHEM 51C or CHEM H52C)

Grading Option: Pass/no pass only.

An exploration of the clinical application of medications to selected disease states. Focus is on an understanding of underlying principles of pharmacology and how this knowledge can be applied to treatment of diseases.

Prerequisite or corequisite: PHRMSCI 170B

Introduces theories and tools of new drug formulations. Particularly new novel therapeutics based on biological materials, pathological characteristics utilized to achieve the maximum efficacy and specificity, and drug delivery systems based on emerging nanotechnology are extensively discussed.

Prerequisite: PHRMSCI 170B

Restriction: Pharmaceutical Sciences Majors have first consideration for enrollment.

Introduction to cancer drug screening using cellular models, and confirmation of comprehensive therapeutic efficacy using a live animal model. Includes basic cell culture, cytotoxicity assays, cell analysis, drug circulation test, and tumor eradication and imaging experiments. Materials fee.

Prerequisite: PHRMSCI 170B and BIO SCI 100

(Ib)

Techniques used in computer-aided drug discovery, including theory behind these techniques and practical applications. Topics include scientific computing; python; classical force fields and simulations; visualization and movie-making; quantum mechanics in drug discovery; molecular dynamics; solvation models; and several others.

Prerequisite: CSE 41 or I&C SCI 31. CSE 42 or I&C SCI 32 is recommended.

Concurrent with PHRMSCI 275.

An introduction of the basics of drug activity and mechanisms. Strategies used to identify lead compounds such as natural product chemistry, combinatorial chemistry, molecular modeling, and high-through put screening. Relationship of molecular structure to pharmacological activity.

Prerequisite: CHEM 51A and CHEM 51B and CHEM 51C and (BIO SCI 98 or CHEM 128)

Same as CHEM 177.

Restriction: Pharmaceutical Sciences Majors have first consideration for enrollment.

An introduction of the basics of drug activity and mechanisms. Strategies used to identify lead compounds such as natural product chemistry, combinatorial chemistry, molecular modeling, and high-through put screening. Relationship of molecular structure to pharmacological activity. Materials fee.

Corequisite: PHRMSCI 177 or CHEM 177.
Prerequisite: CHEM 51A and CHEM 51B and CHEM 51C and BIO SCI 100 and (BIO SCI 98 or CHEM 128)

Same as CHEM 177L.

Restriction: Pharmaceutical Sciences Majors have first consideration for enrollment.

(Ib)

Introduces emerging, ground-breaking technologies in pharmaceutical sciences and medicine, including pharmacogenomics, genome editing, and stem cell and engineered T cell therapies. Explores these novel technologies with both their underlying theories and forward-thinking applications.

Concurrent with PHRMSCI 279.

Provides students with opportunity to develop leadership and professional skills necessary for competitive placement in their chosen industry. Students gain new and field-specific skills outside the classroom environment while participating in a supervised internship for a total of 100 hours.

Grading Option: Pass/no pass only.

Repeatability: May be repeated for credit unlimited times.

Restriction: Seniors only.

Students interested in independent study should arrange with a faculty member to sponsor and supervise such work. A time commitment of three hours per week per unit is expected. A written report is required at the end of each quarter.

Repeatability: May be taken for credit for 4 units.

Original research in the laboratory of Pharmaceutical Sciences faculty. Attendance at regular research group meetings is also generally expected, and a quarterly written report is required. Strongly recommended for students considering research careers and/or graduate degree programs.

Repeatability: May be repeated for credit unlimited times.

Undergraduate honors research in Pharmaceutical Sciences. A student time commitment of 10-15 hours per week is required.

Repeatability: May be repeated for credit unlimited times.

Introduction to nucleic acid and protein structure, dynamics, and function. Topics include analytical methods, molecular evolution, folding, and catalysis.

Same as CHEM 223.

Application of pharmacological principles in disease therapy. Advanced pharmacological mechanisms and in-depth study of drug action. Discussion of several major drug classes/therapeutic strategies: molecular mechanisms of action, physiological consequences of administration, and clinical use.

Restriction: Graduate students only.

Intended to expose students to the primary literature and current research in the field of Pharmaceutical Sciences. Students analyze and present information for discussion. Guest speakers from academia and industry may participate throughout the quarter.

Grading Option: Satisfactory/unsatisfactory only.

Repeatability: May be taken for credit 3 times.

Restriction: Graduate students only. Math and Computational Biology Majors only.

Intended to expose students to the primary literature and current research in the field of Pharmaceutical Sciences. Students analyze and present information for discussion. Guest speakers from academia and industry may participate throughout the quarter.

Prerequisite: PHRMSCI 250A

Grading Option: Satisfactory/unsatisfactory only.

Repeatability: May be taken for credit 3 times.

Restriction: Graduate students only. Math and Computational Biology Majors only.

Intended to expose students to the primary literature and current research in the field of Pharmaceutical Sciences. Students analyze and present information for discussion. Guest speakers from academia and industry may participate throughout the quarter.

Prerequisite: PHRMSCI 250B

Grading Option: Satisfactory/unsatisfactory only.

Repeatability: May be taken for credit 3 times.

Restriction: Graduate students only. Math and Computational Biology Majors only.

Introduction to the concepts and techniques used in pharmacological science. Molecular biology, quantitative and biochemical pharmacology, fluorescent probes, behavior, genetics, animal handling, anatomical and receptor binding analysis, methods for ion channel study, the absorption, distribution, metabolism, and elimination of drugs.

Restriction: Graduate students only.

Ligand-gated ion channels, G protein-coupled receptors, receptor tyrosine kinases, ligand-regulated transcription factors, their signaling mechanisms, trafficking, macromolecular complexes, and physiological responses.

Restriction: Graduate students only.

Mechanisms underlying chemical signaling processes in the brain and periphery. Molecular biology, signal transduction, transmitter synthesis, and inactivation of major neurotransmitter systems. Drugs that act on these major neurotransmitters.

Restriction: Graduate students only.

Population and sample statistics, hypothesis testing, analysis of variance, nonparametric statistics, experimental design, power, and the use of statistical computer software.

Prerequisite: PHARM 251

Restriction: Graduate students only.

Ethical conduct in research including data handling, authorship, conflict of interest, animal rights, handling of misconduct.

Prerequisite: PHARM 299

Repeatability: May be taken for credit 2 times.

Restriction: Graduate students only.

Survey of the genetic and epigenetic basis of inter-subject variability in response to drugs. Covers drug efficacy, safety, and the need for their optimization in pharmacotherapy.Emphasizes genetic mechanisms of polymorphisms in the pharmacokinetics and pharmacodynamics of representative therapeutic drugs.

Restriction: Graduate students only.

Concurrent with PHRMSCI 163.

Provides a comprehensive understanding of RNA in biology. Use of knowledge gained in organic chemistry, biochemistry, genomics, and molecular biology to understand how RNA is integrated into contemporary biology.

Restriction: Graduate students only.

Explores new developments in chemical and synthetic biology that span the areas of chemistry, molecular biology, genetics, bioengineering, systems biology, and computational genomics.

Restriction: Graduate students only.

Provides a mechanism-based overview of pharmacology with strong emphasis on clinical application of pharmacology. Students learn the most recent advances in pharmacology as they relate to drug discovery, development, and clinical application.

Restriction: Graduate students only.

Concurrent with PHRMSCI 170A.

Reserved for current topics of particular interest in areas of pharmaceutical sciences that are not covered by other courses. The subject will vary from year to year, highlighting, for example, significant emerging fields or highly specialized but vital research areas.

Repeatability: Unlimited as topics vary.

Restriction: Graduate students only.

Techniques used in computer-aided drug discovery, including theory behind these techniques and practical applications. Topics include scientific computing; python; classical force fields and simulations; visualization and movie-making; quantum mechanics in drug discovery; molecular dynamics; solvation models; and several others.

Restriction: Graduate students only.

Concurrent with PHRMSCI 175.

Fundamentals of medicinal chemistry covering diverse aspects of drug design, discovery, synthesis, and development. Molecular basis of drug action with an emphasis on the structure-to-function continuum.

Introduces emerging, ground-breaking technologies in pharmaceutical sciences and medicine, including pharmacogenomics, genome editing, and stem cell and engineered T cell therapies. Explores these novel technologies with both their underlying theories and forward-thinking applications.

Concurrent with PHRMSCI 179.

Presentation and discussion of current problems and methods in teaching and research in pharmaceutical sciences.

Repeatability: May be repeated for credit unlimited times.

Restriction: Graduate students only.

Supervised original research or investigation under the direction of an individual faculty member.

Repeatability: May be repeated for credit unlimited times.

Limited to Teaching Assistants.

Grading Option: Satisfactory/unsatisfactory only.

Repeatability: May be repeated for credit unlimited times.

One week (five days, 40 hours) in-residence course offered on the UCI campus. Introduction to pharmacological techniques and current research problems; includes laboratory demonstrations and research seminars.

Restriction: Pharmacology Majors only.

Principles of pharmacology: pharmacodynamics, pharmacokinetics, pharmacogenetics, drug interactions, and toxicity.

Restriction: Pharmacology Majors only.

Molecular basis of drug-receptor interaction. Receptor properties including gene and protein structure, signaling mechanisms, trafficking and physiological effects: G-protein linked receptors, ligand-gated ion channels, receptor tyrosine kinases, nuclear receptors, and ligand regulated transcription factors.

Restriction: Pharmacology Majors only.

Experimental techniques and model systems used in pharmacological research. Receptor analysis, bioassay, molecular biology, in vitro pharmacology, biochemical pharmacology, imaging, electrophysiology, in vivo pharmacology, disease models.

Restriction: Pharmacology Majors only.

Experimental design, data analysis and interpretation. Population and sample statistics, hypothesis testing, analysis of variance, nonparametric statistics, and power calculations.

Restriction: Pharmacology Majors only.

Ethical conduct in research including data handling, authorship, conflict of interest, animal rights, and handling of misconduct.

Restriction: Pharmacology Majors only.

Critical steps involved in discovery and optimization of a new drug. Target selection, relationship of molecular structure to pharmacological activities, screening methods, strategies to identify lead compounds, and preclinical characterization necessary for development of the drug for clinical trials.

Restriction: Pharmacology Majors only.

Topics of current interest in pharmacology; discussion of recent research publications.

Restriction: Pharmacology Majors only.

Capstone research paper on topic of interest in pharmacology.

Restriction: Pharmacology Majors only.

Autonomic and central nervous system pharmacology, including major drug classes and therapeutic uses. Mechanisms underlying chemical signaling processes in the brain and peripheral nervous system, including neurotransmitter synthesis, inactivation, and receptor action.

Restriction: Pharmacology Majors only.

Pharmacology of integrative function and behavior. Drug treatment of pain. Mechanisms of reward, addiction, and drugs of abuse.

Restriction: Pharmacology Majors only.

Basic understanding of drugs used in the prevention and treatment of cardiovascular disease. Mechanisms of action, clinical and adverse effects.

Restriction: Pharmacology Majors only.

Basic understanding of drugs used in endocrine, respiratory, and gastrointestinal conditions, including hormone replacement, contraceptives, and drugs for diabetes, asthma, obesity, ulcer, and gastric reflux. Mechanisms of drug action, clinical and adverse effects.

Restriction: Pharmacology Majors only.

Presentation and discussion of current problems and methods in teaching and research in pharmacology, toxicology, and therapeutics.

Repeatability: May be repeated for credit unlimited times.

Restriction: Graduate students only.

Independent research with Pharmacology and Toxicology faculty.

Repeatability: May be repeated for credit unlimited times.

Restriction: Graduate students only.

The first course in a four-part series that covers interprofessional patient communication, medical interviewing, physical examination, and health promotion. Direct instruction in professionalism, diversity, social determinants of health, kindness, mindfulness, well-being, epidemiology, and biostatistics.

Grading Option: Honors-Pass-Fail.

Restriction: Doctor of Pharmacy students have first consideration for enrollment. Graduate students only.

The second course in four-part series that covers interprofessional communication, medical interviewing, physical examination, and health promotion. Direct instruction in professionalism, diversity, social determinants of health, kindness, mindfulness, well-being, epidemiology, and biostatistics.

Prerequisite: PHMD 200A

Grading Option: Honors-Pass-Fail.

Restriction: Doctor of Pharmacy students have first consideration for enrollment. Graduate students only.

The third course in a four-part series that covers interprofessional communication, medical interviewing, physical examination, and health promotion. Direct instruction in professionalism, diversity, social determinants of health, kindness, mindfulness, well-being, epidemiology, and biostatistics.

Prerequisite: PHMD 200A and PHMD 200B

Grading Option: Honors-Pass-Fail.

Restriction: Doctor of Pharmacy students have first consideration for enrollment. Graduate students only.

The fourth course in a four-part series that covers interprofessional communication, medical interviewing, physical examination, and health promotion. Direct instruction in professionalism, diversity, social determinants of health, kindness, mindfulness, well-being, epidemiology, and biostatistics.

Prerequisite: PHMD 200A and PHMD 200B and PHMD 200C

Grading Option: Honors-Pass-Fail.

Restriction: Doctor of Pharmacy students have first consideration for enrollment. Graduate students only.

The first of a four-part series that covers the function and role of the health care team, Pharmacist Patient Care Process, immunization certification, communication and documentation, informatics, patient safety, interviewing, active listening, management/leadership, careers, resiliency, and student wellness.

Grading Option: Honors-Pass-Fail.

Restriction: Doctor of Pharmacy students have first consideration for enrollment. Graduate students only.

The second of a four-part series that covers the function and roles of the health care team, Pharmacist Patient Care Process, immunization certification, communication and documentation, informatics, patient safety, interviewing, active listening, management/leadership, careers, resiliency, and student wellness.

Prerequisite: PHMD 201A

Grading Option: Honors-Pass-Fail.

Restriction: Doctor of Pharmacy students have first consideration for enrollment. Graduate students only.

The third of a four-part series that covers the function and role of the health care team, Pharmacist Patient Care Process, immunization certification, communication and documentation, informatics, patient safety, interviewing, active listening, management/leadership, careers, resiliency, and student wellness.

Prerequisite: PHMD 201A and PHMD 201B

Grading Option: Honors-Pass-Fail.

Restriction: Doctor of Pharmacy students have first consideration for enrollment. Graduate students only.

The fourth of a four-part series that covers the function and role of the health care team, Pharmacist Patient Care Process, immunization certification, communication and documentation, informatics, patient safety, interviewing, active listening, management/leadership, careers, resiliency, and student wellness.

Prerequisite: PHMD 201A and PHMD 201B and PHMD 201C

Grading Option: Honors-Pass-Fail.

Restriction: Doctor of Pharmacy students have first consideration for enrollment. Graduate students only.

Educates pharmacy students about healthy lifestyle choices, the importance of mental and physical health, and self-care. Provides students with methods and techniques for dealing with the stressors of a professional educational environment and life challenges.

Grading Option: Honors-Pass-Fail.

Restriction: Doctor of Pharmacy students have first consideration for enrollment. Graduate students only.

The study of nonprescription products, complementary/alternative medicine, and non-pharmacological interventions for select self-treatable medical conditions commonly encountered by the pharmacist. Emphasis on the pharmacist's consultant role in product selection and non-pharmacological recommendations.

Prerequisite: PHMD 202A

Grading Option: Honors-Pass-Fail.

Restriction: Doctor of Pharmacy students have first consideration for enrollment. Graduate students only.

Relates to patients' ability to care for themselves with emphasis on the pharmacist's consultant role and continues to explore self-treatable medical conditions commonly encountered by pharmacists, including non-pharmacologic interventions, nonprescription medications, and complementary/alternative products to treat them.

Prerequisite: PHMD 202A and PHMD 202B

Grading Option: Honors-Pass-Fail.

Restriction: Doctor of Pharmacy students have first consideration for enrollment. Graduate students only.

Integrates principles of biomedical and pharmaceutical sciences with evidence-based traditional and non-traditional therapies for management and prevention of disease. Topics include clinical chemistry, clinical toxicology, interprofessional health care, and public health. Covers the central nervous system.

Grading Option: Honors-Pass-Fail.

Restriction: Doctor of Pharmacy students have first consideration for enrollment. Graduate students only.

Integrates principles of biomedical and pharmaceutical sciences with evidence-based traditional and non-traditional therapies for management and prevention of disease. Topics include clinical chemistry, clinical toxicology, interprofessional health care, and public health. Covers the immune system.

Prerequisite: PHMD 203A

Grading Option: Honors-Pass-Fail.

Restriction: Doctor of Pharmacy students have first consideration for enrollment. Graduate students only.

Integrates principles of biomedical and pharmaceutical sciences with evidence-based traditional and non-traditional therapies for management and prevention of disease. Topics include clinical chemistry, clinical toxicology, interprofessional health care, and public health. Covers the cardiovascular and respiratory systems.

Prerequisite: PHMD 203A and PHMD 203B

Grading Option: Honors-Pass-Fail.

Restriction: Doctor of Pharmacy students have first consideration for enrollment. Graduate students only.

Integrates principles of biomedical and pharmaceutical sciences with evidence-based traditional and non-traditional therapies for management and prevention of disease. Topics include clinical chemistry, clinical toxicology, interprofessional health care, and public health. Covers the endocrine system.

Grading Option: Honors-Pass-Fail.

Restriction: Doctor of Pharmacy students have first consideration for enrollment. Graduate students only.

Integrates principles of biomedical and pharmaceutical sciences with evidence-based traditional and non-traditional therapies for management and prevention of disease. Topics include clinical chemistry, clinical toxicology, interprofessional health care, and public health. Covers gastrointestinal, dermatologic, and opthalmologic disorders.

Grading Option: Honors-Pass-Fail.

Restriction: Doctor of Pharmacy students have first consideration for enrollment. Graduate students only.

Integrates principles of biomedical and pharmaceutical sciences with evidence-based traditional and non-traditional therapies for management and prevention of disease. Topics include clinical chemistry, clinical toxicology, interprofessional health care, and public health. Covers gastrointestinal, dermatologic, and opthalmologic disorders.

Grading Option: Honors-Pass-Fail.

Restriction: Doctor of Pharmacy students have first consideration for enrollment. Graduate students only.

Integrates principles of biomedical and pharmaceutical sciences with evidence-based traditional and non-traditional therapies for management and prevention of disease. Topics include clinical chemistry, clinical toxicology, interprofessional health care, and public health. Covers hematology and oncologic disorders.

Grading Option: Honors-Pass-Fail.

Restriction: Doctor of Pharmacy students have first consideration for enrollment. Graduate students only.

Integrates principles of biomedical and pharmaceutical sciences with evidence-based traditional and non-traditional therapies for management and prevention of disease. Topics include clinical chemistry, clinical toxicology, interprofessional health care, and public health. Covers special population and nutritional disorders.

Grading Option: Honors-Pass-Fail.

Restriction: Doctor of Pharmacy students have first consideration for enrollment. Graduate students only.

Exposure to basic statistics and techniques that are commonly found in the medical and pharmacy literature, covering descriptive and inferential statistics. Students learn to choose the most appropriate statistical parametric and non-parametric tests and interpret findings from the literature.

Grading Option: Honors-Pass-Fail.

Restriction: Doctor of Pharmacy students have first consideration for enrollment. Graduate students only.

Addresses development of knowledge, skills, and attitudes required for biomedical inquiry and discovery, including methods for data retrieval, analysis, interpretation, and synthesis.

Prerequisite: PHMD 204A

Grading Option: Honors-Pass-Fail.

Restriction: Doctor of Pharmacy students have first consideration for enrollment. Graduate students only.

Covers distribution of disease and health in groups of people and the factors that influence the distribution, including evaluation of therapeutic and diagnostic treatments and delivery of health care services.

Prerequisite: PHMD 204A and PHMD 204B

Grading Option: Honors-Pass-Fail.

Restriction: Doctor of Pharmacy students have first consideration for enrollment. Graduate students only.

Principles of medical microbiology, immunology, virology, and parasitology. Introduction to classification, morphology, and physiology of microorganisms, particularly those that cause human pathology - bacteria, viruses, fungi, protozoans, parasite, and worms - and the body's immune response.

Prerequisite: PHMD 213 and PHMD 220

Grading Option: Honors-Pass-Fail.

Restriction: Doctor of Pharmacy students have first consideration for enrollment. Graduate students only.

Principles of medical microbiology, immunology, virology, and parasitology. Introduction to classification, morphology, and physiology of microorganisms, particularly those that cause human pathology - bacteria, viruses, fungi, protozoans, parasite, and worms - and the body's immune response.

Prerequisite: PHMD 213 and PHMD 220

Grading Option: Honors-Pass-Fail.

Restriction: Doctor of Pharmacy students have first consideration for enrollment. Graduate students only.

Emphasis on normal human physiology and pathology as it related to clinical chemistry and assessment of disease states with the context of the Pharmacist Patient Care Process. Alterations of clinical chemistry results due to drug therapy are covered.

Prerequisite: PHMD 205A and PHMD 205B

Grading Option: Honors-Pass-Fail.

Restriction: Doctor of Pharmacy students have first consideration for enrollment. Graduate students only.

Provides an overview of the basic principles of pharmacology, covering pharmacodynamics - effects of drugs on the body - and pharmacokinetics - the process by which a drug is absorbed, distributed, metabolized, and excreted by the body.

Prerequisite: PHMD 220 and PHMD 277A and PHMD 277B

Grading Option: Honors-Pass-Fail.

Restriction: Doctor of Pharmacy students have first consideration for enrollment. Graduate students only.

Covers the framework, principles, and core responsibilities of public health research and practice from multidisciplinary perspectives. It also provides the necessary foundation for further studies using crosscutting approaches essential for public health practice.

Grading Option: Honors-Pass-Fail.

Restriction: Doctor of Pharmacy students have first consideration for enrollment. Graduate students only.

Concurrent with PUBH 200.

Walks students through the basics of genetics and genomics. Particular emphasis is placed on the use of genetics or genetic testing to assist in patient treatment regimens and evaluation of disease.

Grading Option: Honors-Pass-Fail.

Restriction: Doctor of Pharmacy students have first consideration for enrollment. Graduate students only.

Topics include the biological, chemical and cellular roles of carbohydrates, lipids, proteins, nucleic acids, hormones, enzymes and vitamins. In addition, the chemical and cellular basis of digestion, intermediary metabolism, biological oxidation and metabolic antagonism are discussed.

Grading Option: Honors-Pass-Fail.

Restriction: Doctor of Pharmacy students have first consideration for enrollment. Graduate students only.

An introduction to California and federal legal requirements that impact pharmacy practice, emphasizing the legal and ethical principles applied by pharmacists in their decision-making. Explores approaches for resolving ethical dilemmas in patient care.

Grading Option: Honors-Pass-Fail.

Restriction: Doctor of Pharmacy students have first consideration for enrollment. Graduate students only.

Introduces students to the organization, financing, and delivery of health care services in the U.S. The relationship of providers, patients, payers, etc., are analyzed. Management and research principles utilized to manage drug therapy are introduced.

Grading Option: Honors-Pass-Fail.

Restriction: Doctor of Pharmacy students have first consideration for enrollment. Graduate students only.

Fundamentals of pharmacology and mechanisms of action are reinforced and applied to learn the clinical effects of acute/chronic exposure derived from environmental, dietary, occupational and pharmaceutical sources. Students focus on information literacy skills and clinical management of poisonings.

Prerequisite: PHMD 210

Grading Option: Honors-Pass-Fail.

Restriction: Doctor of Pharmacy students have first consideration for enrollment. Graduate students only.

Concepts of physiology and mechanisms of body function at various levels of organization from cellular to organ systems. Emphasis on quantitative understanding of various body processes. Human anatomy is integrated with physiological concepts. Anatomic-physiologic relationships facilitated through virtual labs.

Grading Option: Honors-Pass-Fail.

Restriction: Doctor of Pharmacy students have first consideration for enrollment. Graduate students only.

The first in a foundational series designed to develop an understanding of the science behind drug formulation, mechanisms, pharmacokinetics and interconnections with the Pharmacist Patient Care Process.

Grading Option: Honors-Pass-Fail.

Restriction: Doctor of Pharmacy students have first consideration for enrollment. Graduate students only.

The second course in a foundational series designed to develop an understanding of the science behind drug formulation, mechanisms, pharmacokinetics and interconnections with the pharmacist patient care process. Topics include drug substances, dosage forms, and therapeutic effects. Includes laboratory.

Prerequisite: PHMD 274A

Grading Option: Honors-Pass-Fail.

Restriction: Doctor of Pharmacy students have first consideration for enrollment. Graduate students only.

The final course in a foundational series designed to develop an understanding of the science behind drug formulation, mechanisms, pharmacokinetics,and interconnections with the Pharmacist Patient Care Process. In laboratory, students perform pharmacokinetic modeling, drug screening, and comprehensive therapeutic efficacy.

Prerequisite: PHMD 274A and PHMD 274B

Grading Option: Honors-Pass-Fail.

Restriction: Doctor of Pharmacy students have first consideration for enrollment. Graduate students only.

Application of organic chemistry, biochemistry, molecular biology, physical chemistry, pharmacology, and physiology to understand the theory and mechanics of modern day medicinal chemistry. Topics include receptor-protein structure, dynamics, and interactions; drug development and design; and pharmacodynamics, and pharmacokinetics.

Grading Option: Honors-Pass-Fail.

Restriction: Doctor of Pharmacy students have first consideration for enrollment. Graduate students only.

Walks students through medicinal chemistry, broadly defined. Students utilize the knowledge gained in organic chemistry, biochemistry, molecular biology, physical chemistry, pharmacology and physiology in an integrated fashion as applied to modern medicinal chemistry. Continuation of Medicinal Chemistry I.

Prerequisite: PHMD 277A

Grading Option: Honors-Pass-Fail.

Restriction: Doctor of Pharmacy students have first consideration for enrollment. Graduate students only.

Provides students an opportunity to develop independent thinking, with particular focus on maturing analytical skills. Students are encouraged to develop an independent project, with a mentor, to study pharmacy-related aspects of multiple areas. First phase identifies project focus.

Grading Option: Honors-Pass-Fail.

Restriction: Doctor of Pharmacy students have first consideration for enrollment. Graduate students only.

Provides students an opportunity to develop independent thinking, with particular focus on maturing analytical skills. Students develop an independent project, with a mentor, to study pharmacy-related aspects of multiple areas. Phase 2 focuses on final evaluation of project.

Grading Option: Honors-Pass-Fail.

Restriction: Doctor of Pharmacy students have first consideration for enrollment. Graduate students only.

Reinforces and assesses student pharmacist’s performance on cumulative learning outcomes; pre-APPE and APPE knowledge, skills, and attitudes; entrustable professional activities; team- and practice-readiness; and to demonstrate that student pharmacists are achieving outcomes required by the ACPE.

Grading Option: Honors-Pass-Fail.

Restriction: Doctor of Pharmacy students have first consideration for enrollment. Graduate students only.

Designed to engage students and expose them to seminar speakers that come to discuss research or case studies in pharmaceutical sciences and pharmacy.

Grading Option: Honors-Pass-Fail.

Repeatability: May be repeated for credit unlimited times.

Restriction: Doctor of Pharmacy students have first consideration for enrollment. Graduate students only.